What does the term "off-label" mean concerning prescription medications?

The term "off-label" refers to the use of a medication in a way that is not explicitly specified in the FDA's approved labeling. This means that a veterinarian may prescribe a medication for a condition or a species that it has not been specifically approved for by the FDA, based on their clinical judgment and experience. Off-label use is a common practice in veterinary medicine, as it allows veterinarians the flexibility to tailor treatments to the unique needs of their patients, taking into consideration factors such as species differences, individual health conditions, and the latest scientific research.

For example, a veterinarian might choose to prescribe a drug for a condition in a species for which the drug wasn't originally studied or approved, based on evidence of its effectiveness from clinical experience or scientific literature. The ability to use drugs off-label is an essential component of providing comprehensive veterinary care, as it can sometimes lead to improved outcomes for patients.